A Flexible Regimen of Combination Antihypertensive Therapy for Lower Blood Pressure to the Lower Target Level. Viewpoint of Cardiologist and Clinical Pharmacologist

Author:

Gilyarevskiy S. R.1,Golshmid M. V.1,Zaharova G. Yu.1,Kuzmina I. M.2,Sinitsina I. I.1

Affiliation:

1. Russian Medical Academy of Continuing Professional Education

2. Sklifosovsky Research Institute of Emergency Medicine

Publisher

Stolichnaya Izdatelskaya Kompaniyaizdat

Subject

Pharmacology (medical),Cardiology and Cardiovascular Medicine

Reference33 articles.

1. Simpkin A.L., Schwartzstein R.M. Tolerating Uncertainty - Tie Next Medical Revolution? N Engl J Med. 2016;37:1713-15. doi:10.1056/NEJMpl606402.

2. Whelton P.K., Carey R.M., Aronow W.S., et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension. 2018;71 :e13-e115. doi: 10.1161/HYP,0000000000000065.

3. Williams B., Mancia G., Spiering W., et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018;39:3021-104. doi:10.1093/eurheartj/ehy339.

4. SPRINT Research Group. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med. 2015;373:21 03-16. doi:10.1056/NEJMoa1511939.

5. Phillips R.A., Xu J., Peterson L.E., et al. Impact of Cardiovascular Risk on the Relative Benefit and Harm of Intensive Treatment of Hypertension. J Am Coll Cardiol. 2018;71:1601-10. doi:10.1016/j.jacc.2018.01.074.

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