Alteration in the clinical manifestations of monkeypox in the presence of HIV

Abstract

Introduction: The monkeypox virus is an orthopox virus belonging to the Poxiviridae family, being a zoonotic infection, with prevalence in the male population, on reproductive age, mainly in men who have sex with men. The virus enters through direct contact with infected skin, body fluids or respiratory droplets. The clinic begins with general prodromal symptoms, followed by a phase of skin lesions in different areas of the body. Objective: To compare the development of monkeypox infection in immunocompromised individuals with respect to a normal course of the disease. Materials and methods: Review of bibliographic data from 33 scientific articles, using databases such as PUBMED and Google Scholar, with the keywords "Monkeypox", "2022", "Clinical manifestations" that included complete characteristics of the virus and having a range of 5 years old as a limit. Results: There is evidence that demonstrates the existence of a coinfection of monkeypox with HIV, increasing the possibility of being a case of opportunism, resulting in an atypical picture in the evolution of the disease. Which begins with rash in genital area with pain and pustules, 3 days later general symptoms of an infectious process are added. Ending with diffuse pruritus accompanied by pustules on the back and extremities. Conclusions: A relationship was determined between seropositive male patients with atypical lesions of the disease, affecting the symptomatologic evolution and a correct diagnosis.