An Extra Amino Acid Residue in Transmembrane Domain 10 of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Is Required for Efficient Ion-coupled Transport-Reference-Cited by-同舟云学术

An Extra Amino Acid Residue in Transmembrane Domain 10 of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Is Required for Efficient Ion-coupled Transport

Published:2017-03 Issue:13 Volume:292 Page:5418-5428
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Dayan Oshrat,Nagarajan Anu,Shah Raven,Ben-Yona Assaf,Forrest Lucy R.,Kanner Baruch I.

Funder

Israel Science Foundation

Rosetrees Trust

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference53 articles.

1. The family of Na+/Cl− neurotransmitter transporters;Nelson;J. Neurochem,1998

2. Sodium-coupled neurotransmitter transporters;Kanner;Chem. Rev,2008

3. GAT1 (GABA:Na+:Cl−) cotransport function: steady state studies in giant Xenopus oocyte membrane patches;Lu;J. Gen. Physiol,1999

4. γ-Aminobutyric acid transport in reconstituted preparations from rat brain: coupled sodium and chloride fluxes;Keynan;Biochemistry,1988

5. Electrogenic uptake of γ-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes;Kavanaugh;J. Biol. Chem,1992

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