Site-specific Mutagenesis and Domain Substitutions in the Loading Module of the Nystatin Polyketide Synthase, and Their Effects on Nystatin Biosynthesis in Streptomyces noursei-Reference-Cited by-同舟云学术

Site-specific Mutagenesis and Domain Substitutions in the Loading Module of the Nystatin Polyketide Synthase, and Their Effects on Nystatin Biosynthesis in Streptomyces noursei

Published:2003-04 Issue:17 Volume:278 Page:14913-14919
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Brautaset Trygve,Borgos Sven E.F.,Sletta Håvard,Ellingsen Trond E.,Zotchev Sergey B.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference25 articles.

1. Modular organization of genes required for complex polyketide biosynthesis

2. The loading domain of the erythromycin polyketide synthase is not essential for erythromycin biosynthesis in Saccharopolyspora erythraea

3. Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase

4. A chain initiation factor common to both modular and aromatic polyketide synthases

5. Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum

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