A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference38 articles.
1. The role of protein phosphorylation in human health and disease. The Sir Hans Krebs Medal Lecture;Cohen;Eur. J. Biochem,2001
2. Protein-tyrosine phosphatases–from housekeeping enzymes to master regulators of signal transduction;Tonks;FEBS J,2013
3. Targeting cancer with kinase inhibitors;Gross;J. Clin. Invest,2015
4. Targeting tyrosine phosphatases: time to end the stigma;Stanford;Trends Pharmacol. Sci,2017
5. PTP1B: a simple enzyme for a complex world;Feldhammer;Crit. Rev. Biochem. Mol. Biol,2013
Cited by 102 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Regulation of protein phosphorylation by PTPN2 and its small-molecule inhibitors/degraders as a potential disease treatment strategy;European Journal of Medicinal Chemistry;2024-11
2. Advances in small-molecule insulin secretagogues for diabetes treatment;Biomedicine & Pharmacotherapy;2024-09
3. Deadly excess copper;Redox Biology;2024-09
4. The expanding landscape of canonical and non-canonical protein phosphorylation;Trends in Biochemical Sciences;2024-09
5. Protein tyrosine phosphatase 1B in metabolic and cardiovascular diseases: from mechanisms to therapeutics;Frontiers in Cardiovascular Medicine;2024-08-22
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3