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Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry

  • Published:2019-05 Issue:5 Volume:18 Page:968-981
  • ISSN:1535-9476
  • Container-title:Molecular & Cellular Proteomics
  • language:en
  • Short-container-title:Molecular & Cellular Proteomics

Author:

Lapek John D.,Jiang Zhenze,Wozniak Jacob M.,Arutyunova Elena,Wang Steven C,Lemieux M. Joanne,Gonzalez David J.,O'Donoghue Anthony J.

Funder

American Cancer Society

Ray Thomas Edwards Foundation

HHS | NIH | National Institute of General Medical Sciences

UC | University of California, San Diego

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Analytical Chemistry

Reference78 articles.

1. Handbook of proteolytic enzymes;Rawlings;Academic Press, London; Boston,2013

2. Targeting proteases: successes, failures and future prospects;Turk;Nat. Rev. Drug Discov,2006

3. Protease-activated drug development;Choi;Theranostics,2012

4. Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries;Harris;Proc. Natl. Acad. Sci. U.S.A,2000

5. Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates;Poreba;Cell Death Differ,2014
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