Integrin α6β4 Promotes Autocrine Epidermal Growth Factor Receptor (EGFR) Signaling to Stimulate Migration and Invasion toward Hepatocyte Growth Factor (HGF)

Author:

Carpenter Brittany L.,Chen Min,Knifley Teresa,Davis Kelley A.,Harrison Susan M.W.,Stewart Rachel L.,O'Connor Kathleen L.

Funder

American Cancer Society

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference62 articles.

1. Upregulation and redistribution of integrin α6β4 expression occurs at an early stage in pancreatic adenocarcinoma progression;Cruz-Monserrate;Mod. Pathol,2007

2. Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer;Logsdon;Cancer Res,2003

3. β4 integrin is required for hemidesmosome formation, cell adhesion and cell survival;Dowling;J. Cell Biol,1996

4. A signaling adapter function for α6β4 integrin in the control of HGF-dependent invasive growth;Trusolino;Cell,2001

5. α6β4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancer;Gilcrease;J. Exp. Clin. Cancer Res,2009

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