Secretome Analysis of an Osteogenic Prostate Tumor Identifies Complex Signaling Networks Mediating Cross-talk of Cancer and Stromal Cells Within the Tumor Microenvironment

Author:

Lee Yu-Chen,Gajdosik Martina Srajer,Josic Djuro,Clifton James G.,Logothetis Christopher,Yu-Lee Li-Yuan,Gallick Gary E.,Maity Sankar N.,Lin Sue-Hwa

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Analytical Chemistry

Reference36 articles.

1. Osteoblasts in prostate cancer metastasis to bone;Logothetis;Nat. Rev. Cancer,2005

2. Prostate cancer cells promote osteoblastic bone metastases through Wnts;Hall;Cancer Res,2005

3. Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms;Li;J. Clin. Invest,2008

4. BMP4 promotes prostate tumor growth in bone through osteogenesis;Lee;Cancer Res,2011

5. 16-kDa prolactin inhibits endothelial cell migration by down-regulating the Ras-Tiam1-Rac1-Pak1 signaling pathway;Lee;Cancer Res,2007

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