The conserved threonine-rich region of the HCF-1PRO repeat activates promiscuous OGT:UDP-GlcNAc glycosylation and proteolysis activities
Author:
Funder
Swiss National Science Foundation
Wellcome Trust Investigator Award
European Molecular Biology Organization
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference24 articles.
1. O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1;Capotosti;Cell,2011
2. HCF-1 is cleaved in the active site of O-GlcNAc transferase;Lazarus;Science,2013
3. How the glycosyltransferase OGT catalyzes amide bond cleavage;Janetzko;Nat. Chem. Biol,2016
4. Proteolytic cleavage driven by glycosylation;Kötzler;J. Biol. Chem,2016
5. O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis;Schimpl;Nat. Chem. Biol,2012
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