Dual-reporter high-throughput screen for small-molecule in vivo inhibitors of plasminogen activator inhibitor type-1 yields a clinical lead candidate
Author:
Funder
HHS | NIH | National Heart, Lung, and Blood Institute
University of Michigan Cancer Center
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference46 articles.
1. Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function;Irving;Genome Res,2000
2. PAI-1 in tissue fibrosis;Ghosh;J. Cell. Physiol,2012
3. Intramural plasminogen activator inhibitor type-1 and coronary atherosclerosis;Sobel;Arterioscler. Thromb. Vasc. Biol,2003
4. The role of plasminogen activator inhibitor type-1 in fibrosis;Flevaris;Semin. Thromb. Hemost,2017
5. Impaired fibrinolytic system in ApoE gene-deleted mice with hyperlipidemia augments deep vein thrombosis;Diaz;J. Vasc. Surg,2012
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