PET/CT with ⁶⁸Ga-FAPI in the Diagnosis of Cancer of Unknown Primary Localization. Clinical Case

Abstract

   Purpose: Analysis of a clinical case of detection the primary focus in a patient with metastatic liver damage from cancer of unknown primary localization using PET/CT with 68Ga-FAPI.   Material and methods: A patient with metastatic liver damage from CUP underwent a set of diagnostic methods, according to the results of which the primary focus was not detected. PET/CT with 68Ga-FAPI revealed the primary focus, which was localize in the left breast and did not accumulate 18F-FDG. According to mammography, the formation in the left breast was regard as benign changes (BI-RADS-2). According to the results of histological examination, the node in the left breast is invasive ductal cancer.   Conclusion: PET/CT with 68Ga-FAPI can potentially surpass PET/CT with 18F-FDG in the detection of primary tumors in metastases from cancer of unknown primary localization.