Abstract
Embracing the philosophical condition of epistemology in research has led to identifying and understanding the meaning and nature of diabetes and the use of protein-polysaccharides complexes in the treatment of diabetes. The research approach is purely qualitative; thereby, postmodern epistemological assumptions were made from the theory of knowledge on diabetes, its conditions and symptoms, effects, protein and polysaccharides characteristics. The research develops knowledge on using protein-polysaccharides obtained mainly from plant species like mushrooms and pumpkins generated from credible and valid knowledge connected from observable justification, beliefs and truths from scholarly material. In the process, knowledge has been created identifying that protein-polysaccharides complexes contain polysaccharides that have proven to possess hypoglycaemic activity that reduces hyperglycaemia leading to an increase in insulin secretion and reduction of blood glucose.