Comparing flickering and pulsed chromatic pupil light responses

Author:

Tripolone María Constanza1ORCID,Issolio Luis Alberto12,Agüero Carlos3,Lavaque Alejandro3,Cao Dingcai4,Barrionuevo Pablo Alejandro1ORCID

Affiliation:

1. Consejo Nacional de Investigaciones Científicas y Técnicas–Universidad Nacional de Tucumán

2. Universidad Nacional de Tucumán

3. Centro de Especialidades Oftalmológicas

4. University of Illinois at Chicago

Abstract

The pupil light reflex (PLR) can serve as a biomarker of the photoreceptor function. Protocols for chromatic PLR consider mostly pulsed stimulation. A more sophisticated and promising technique is based on the PLR to flickering stimulation. Our aim was to compare flickering PLR (fPLR) and pulsed PLR (pPLR) parameters to validate the fPLR paradigm. Two different experiments were carried out in young participants to compare parameters of chromatic pupillary measurements under flickering and pulsed conditions. We found that the fPLR amplitude parameter was significantly associated with the pPLR transient constriction parameter. Also, for some conditions, pulse parameters can be identified directly in the fPLR recordings.

Funder

Consejo Nacional de Investigaciones Científicas y Técnicas

Agencia Nacional de Promoción Científica y Tecnológica

Publisher

Optica Publishing Group

Subject

Computer Vision and Pattern Recognition,Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Pupil reactivity;Reference Module in Neuroscience and Biobehavioral Psychology;2024

2. Systems for selective stimulation of retinal pathways;Optica Pura y Aplicada;2023-06-30

3. Photoreceptor contributions to the human pupil light reflex;Journal of Photochemistry and Photobiology;2023-06

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