Affiliation:
1. University of Washington
Abstract
The use of optical attenuation coefficients (OAC) in optical coherence
tomography (OCT) imaging of the retina has improved the segmentation
of anatomic layers compared with traditional intensity-based
algorithms. Optical attenuation correction has improved our ability to
measure the choroidal thickness and choroidal vascularity index using
dense volume scans. Algorithms that combine conventional
intensity-based segmentation with depth-resolved OAC OCT imaging have
been used to detect elevations of the retinal pigment epithelium (RPE)
due to drusen and basal laminar deposits, the location of
hyperpigmentation within the retina and along the RPE, the
identification of macular atrophy, the thickness of the outer retinal
(photoreceptor) layer, and the presence of calcified drusen. OAC OCT
algorithms can identify the risk-factors that predict disease
progression in age-related macular degeneration.
Funder
Carl Zeiss Meditec
Research to Prevent
Blindness
National Eye Institute
Subject
Atomic and Molecular Physics, and Optics,Biotechnology
Cited by
1 articles.
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