Time-resolved fluorescence studies of porphycene and tetrasulfonated phthalocyanine dyes in varying solvents

Abstract

Various chemicals used for photodynamic therapy, a promising treatment for cancer, exhibit high fluorescence yields which can be used for tumour detection. For a chosen few such compounds fluorescence lifetimes, absorption, and steady state fluorescence spectra were measured at different concentrations (ranging from 10-5 M to 10-8 M) in a variety of solvents The lifetimes were repeated at three different concentrations (ranging from 10-5 M to 10-6 M) in suspensions of 3T3 fibroblast cells.