Potency and plasma protein binding of drugs in vitro—a potentially misleading pair for predicting in vivo efficacious concentrations in humans-Reference-Cited by-同舟云学术

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Potency and plasma protein binding of drugs in vitro—a potentially misleading pair for predicting in vivo efficacious concentrations in humans

Published:2019 Issue:4 Volume:23 Page:231
ISSN:1226-4512
Container-title:The Korean Journal of Physiology & Pharmacology
language:en
Short-container-title:Korean J Physiol Pharmacol

Author:

Yim Dong-Seok¹²

Affiliation:

1. Department of Clinical Pharmacology and Therapeutics, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul 06591, Korea.

2. PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

Publisher

The Korean Physiological Society and The Korean Society of Pharmacology

Subject

Pharmacology,Physiology

Link

https://synapse.koreamed.org/pdf/10.4196/kjpp.2019.23.4.231

Reference18 articles.

1. The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery

2. Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds

3. A Phase I and Pharmacokinetic Trial of Erlotinib in Combination with Weekly Docetaxel in Patients with Taxane-Naive Malignancies

4. Therapeutic drug monitoring-antiepileptic drugs

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