Study of Sporo-Lex probiotic effectiveness on pigs

Abstract

Food sorbents are veterinary drugs and feed additives designed to bind toxic substances in the gastrointestinal tract and remove them from the body of animals. The goal of the work is to conduct a study of the effectiveness of the veterinary drug Sporo-Lex for use on pigs. Materials and methods. Probiotic Sporo-Lex is a mixture of probiotic cultures of Bacillus licheniformis VK-25 and Bacillus subtilis MK-3 on a natural standardized sorbent (montmorillonite rock of the Volodymyretsk city deposit). The research was carried out in the conditions of a private pig farm on 74-day-old landrace pigs, while 76 animals were involved in the experiment (36 heads - experimental and 36 heads - control), groups were formed according to the principle of analogs. The number of erythrocytes, hemoglobin content, bactericidal activity of blood serum (BABS), level of phagocytic activity of leukocytes, phagocytic index, as well as the concentration of Escherichia coli bacteria in feces were determined. Results of research and discussion. As a result of the study of the dynamics of changes in the number of erythrocytes in the blood of experimental and control subjects, it was established that on the 13th day, the number of erythrocytes in the blood of the animals treated with Sporo-Lex significantly increased on the 25th day of the study. The results of the quantitative determination of the level of hemoglobin in the blood of the experimental and control groups of pigs indicate a significant increase in the level of hemoglobin in the experimental group, on the 13th day, in accordance with the control. At the same time, the probability level was 99.6% for experimental group 1 and 99.9% for group 2. A significant increase in the BABS of pigs was recorded from the 13th day of the experiment. At the same time, the level of probability was 98%. According to the obtained results of the study of the influence of the probiotic Sporo-lex on the level of phagocytic activity of blood leukocytes of pigs, it was established that its significant increase was observed on the 4th day of the experiment, in the experimental group it was (42±1.75)%, while in the control group – (34±1.75) %.Probiotic Sporo-Lex when applied to pigs, according to the obtained data, in the experimental group, a significant increase in the phagocytic blood index was observed on the 4th day, and amounted to (2.8±0.1)%, while in the control this indicator was (2.5±0.12) %. Regarding the influence of the probiotic Sporo-Lex on the concentration of bacteria of the Escherichia coli group in feces, it was established that in the animals of the experimental group, on the 25th day, a significant decrease in the concentration of coli group bacteria was observed to (3.2±0.7)×105, while in the animals of the control group group their concentration was (9.8±0.3)×105. According to the research results, it was established that the probiotic Sporo-Lex in the animals of the experimental group increases the average statistical weight by 4.94 kg on the 84th day and by 4.71 kg on the 112th day in comparison with the control. Conclusions. It has been experimentally proven that the drug Sporo-lex reliably increases the level of BABS, an increase in the phagocytic activity of leukocytes is observed and induces an increase in the phagocytic index of leukocytes compared to the control. It is advisable to use the drug as a biological feed additive with a directed adaptogenic and immunocorrective effect on the fattening of young farm animals. Key words: Sporo-lex, probiotic, sorbent, efficiency, animals, piglets, bacteria of the group of Escherichia coli.