LOW PULSOXIMETRY AS A MANIFESTATION OF CONGENITAL HEMOGLOBINOPATHIES. THE CASE OF HEMOGLOBIN BONN IN THE TVER REGION-Reference-Cited by-同舟云学术

LOW PULSOXIMETRY AS A MANIFESTATION OF CONGENITAL HEMOGLOBINOPATHIES. THE CASE OF HEMOGLOBIN BONN IN THE TVER REGION

Published:2017 Issue:3 Volume: Page:76-80
ISSN:1726-9806
Container-title:Annals of critical care
language:
Short-container-title:Вестник интенсивной терапии

Author:

Ситкин С.И.¹^ORCID,Поздняков О.Б.¹^ORCID,Янков В.Г.²^ORCID,Хижняк Б.И.²^ORCID

Affiliation:

1. ФГБОУ ВО «Тверской государственный медицинский университет» Минздрава России

2. ГБУЗ «Областной клинический перинатальный центр им. Е.М. Бакуниной»

Abstract

Pulse oximetry is the most common method of monitoring respiratory failure. A decrease in SpO2 indices is a sign of hy- poxemia. Abnormal hemoglobins, with a hereditary mutation in α-globin or in β-globin, can lead to falsely low saturation of hemoglobin with oxygen. The frequency of this pathology occur- rence in the population is unknown. This article reviews inter- national publications on this issue and cites the case of heredi- tary hemoglobinopathy (Hb Bonn) in the parturient, her father and her son. All patients showed a decrease in osmotic resistance of red blood cells by 30 %. The son of the woman at the age of three years suffered from the hemolytic-uremic syndrome, which required renal replacement therapy. The knowledge of abnor- mal hemoglobins accompanied by low pulsoximetry will help to avoid medical errors.

Publisher

Practical Medicine Publishing House

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