Prevalence of anti-SARS-CoV-2 antibodies and associated factors in healthcare workers of a Mexican Covid-19 hospital
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Published:2022-07-08
Issue:4, jul-ago
Volume:64
Page:348-356
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ISSN:1606-7916
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Container-title:Salud Pública de México
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language:
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Short-container-title:Salud Publica Mex
Author:
Herrera-Ortiz Antonia,Rojas-Delgado Héctor Ugo,García-Cisneros Santa,Xibille-Friedmann Daniel X,Martínez-Barnetche Jesús,Olamendi-Portugal María,González-Sánchez Hilda Minerva,Sánchez-Alemán Miguel Ángel
Abstract
Objective. To determine the prevalence of SARS-CoV-2 antibodies among healthcare workers (HCW) and to identify factors associated with infection. Materials and methods. A cross-sectional study was conducted in a Covid-19 hospital in Morelos, Mexico. Antibodies against SARS-CoV-2 spike and nucleocapsid proteins were detected by ELISA. A bivariate and multivariable Poisson regression model were performed to identify factors associated with infection. Results. Among all participants, 31% had anti-SARS-CoV-2 antibodies, while only 13.1% had reported a history of positive RT-PCR. Individuals who reported cohabiting with someone with Covid-19, and those who had a previous RT-PCR test, were more likely to be seropositive. Laboratory personnel had the lowest seroprevalence (12.0%), while social workers had the highest (35.7%). Conclusions. The results of this study show the seroprevalence of SARS-CoV-2 antibodies among HCW in a hospital in Mexico, and underline the importance of serological tests for a better estimate of prevalence in health systems where only symptomatic cases are recorded.
Publisher
Instituto Nacional de Salud Publica
Subject
Public Health, Environmental and Occupational Health,Public Health, Environmental and Occupational Health
Cited by
1 articles.
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