Novel HDAC6 selective inhibitors with 4-aminopiperidine-1- carboxamide as the core structure enhanced growth inhibitory activity of bortezomib in MCF-7 cells
Author:
Affiliation:
1. Department of Pharmacology, School of Pharmacy, Qingdao University
2. Department of Medicinal Chemistry, School of Pharmacy, Qingdao University
Publisher
International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine,Health (social science)
Link
https://www.jstage.jst.go.jp/article/bst/13/1/13_2019.01049/_pdf
Reference24 articles.
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2. 2. Secrist JP, Zhou X, Richon VM. HDAC inhibitors for the treatment of cancer. Curr Opin Investig Drugs. 2003; 4:1422-1427.
3. 3. Zhang Y, Fang H, Jiao J, Xu W. The structure and function of histone deacetylases: The target for anti-cancer therapy. Curr Med Chem. 2008; 15:2840-2849.
4. 4. West AC, Johnstone RW. New and emerging HDAC inhibitors for cancer treatment. J Clin Invest. 2014; 124:30-39.
5. 5. Zhang L, Han Y, Jiang Q, Wang C, Chen X, Li X, Xu F, Jiang Y, Wang Q, Xu W. Trend of histone deacetylase inhibitors in cancer therapy: Isoform selectivity or multitargeted strategy. Med Res Rev. 2015; 35:63-84.
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