Affiliation:
1. Department of Internal Medicine, Medical Research Institute, Alexandria University, Alexandria, Egypt
2. Department of Chemical Pathology, Medical Research Institute, Alexandria University, Alexandria, Egypt
Abstract
Background
Helicobacter pylori is a common pathogen that is prevalent worldwide, it is known by its effect on gastrointestinal tract, as it causes gastritis, gastric ulcer, and gastric carcinoma.
H. pylori infection contributed to other nongastric systemic diseases including cardiovascular and metabolic diseases.
Some epidemiologic studies, found that H. pylori infection is related to cardiac risks such as dyslipidemia, hypertension, obesity, and diabetes mellitus, but other studies failed to find any correlation. Whether H. pylori infection is contributing to cardiovascular disease by affecting its risk factors or not; need further studies.
Aim
Study the effect of H. pylori infection on lipid metabolism as one of the cardiovascular risk factors, independent of other risks.
Patients and Methods
Thirty patients having H. pylori infection and 30 patients without infection were examined for their lipid profile, provided that there is no other risk factor for cardiovascular disease, and the patients are not on treatment for dyslipidemia.
Results
No correlation between H. pylori infection and dyslipidemia was found.
Conclusion
Infection with H. pylori is not related to changes in lipid profile provided that there are no other risk factors for dyslipidemia.