Polymerization of the triphosphates of AraC, 2′,2′-difluorodeoxycytidine (dFdC) and OSI-7836 (T-araC) by human DNA polymerase α and DNA primase

Author:

Richardson Katherine A.,Vega Tanya P.,Richardson Frank C.,Moore Chad L.,Rohloff John C.,Tomkinson Blake,Bendele Raymond A.,Kuchta Robert D.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference32 articles.

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2. A phase I trial of the novel nucleoside analog OSI-7836 given on days 1 and 8 every 3 weeks;Siu;Eur J Cancer,2003

3. de Jonge M, O’Donnell A, Verweij J, Chick J, Hanwell J, Schothorst K, et al. Phase I Evaluation of OSI-7836—a New Nucleoside Analogue—Using Two Administration Schedules. AACR-NCI-EORTC Meeting, November 2003.

4. Comparison of the antitumor activity of gemcitabine and AraC in a panel of human breast, colon, lung, and pancreatic xenograft models;Merriman;Invest New Drugs,1996

5. Metabolism of 4′-thio-B-d-arabinosylcytosine in CEM cells;Parker;Biochem. Pharmacol.,2000

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