Main contribution of the cytochrome P450 isoenzyme 1A2 (CYP1A2) to N-demethylation and 5-sulfoxidation of the phenothiazine neuroleptic chlorpromazine in human liver—A comparison with other phenothiazines

Author:

Wójcikowski Jacek,Boksa Jan,Daniel Władysława A.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference30 articles.

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4. Correlation of activity of chlorpromazine and respective hydroxy, dimethoxy and sulphoxide analogues on dopamine, muscarinic, histamine and calmoduline sites of action;Palmer;Xenobiotica,1988

5. Chlorpromazine metabolism in extracts of liver and small intestine from guinea pig and from man;Hartmann;Drug Metab Dispos,1983

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