Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305

Author:

Augustin Ewa,Moś-Rompa Anna,Skwarska Anna,Witkowski Jacek M.,Konopa Jerzy

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference34 articles.

1. 8-Substituted 5-[(aminoalkyl)amino]-6H-v-triazolo[4,5,1-de]acridin-6-ones as potential antineoplastic agents;Chołody;J Med Chem,1990

2. Experimental antitumor activity and toxicity of the selected triazolo- and imidazoacridinones;Kuśnierczyk;Arch Immunol Ther Exp,1994

3. The antitumor triazoloacridone C-1305 is a topoisomerase II poison with unusual properties;Lemke;Mol Pharmacol,2004

4. Specific inhibition of the growth-associated alpha isoform of topoisomerase II by the novel anticancer triazoloacridinone C-1305;Lemke;Eur J Cancer,2002

5. Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout cells to antitumor triazoloacridone C-1305 is associated with permanent G2 cell cycle arrest;Węsierska-Gądek;Cancer Res,2004

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