Effective sample size estimation for a mechanical ventilation trial through Monte-Carlo simulation: Length of mechanical ventilation and Ventilator Free Days

Author:

Morton S.E.ORCID,Chiew Y.S.,Pretty C.,Moltchanova E.,Scarrott C.,Redmond D.ORCID,Shaw G.M.,Chase J.G.

Funder

Royal Society of New Zealand

Publisher

Elsevier BV

Subject

Applied Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Modelling and Simulation,General Medicine,Statistics and Probability

Reference21 articles.

1. ACCP consensus conference - mechanical ventilation;Slutsky;Chest,1993

2. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome;Brower;New Engl. J. Med.,2004

3. Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial;Meade;Jama,2008

4. For the expiratory pressure (express) study group positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome;Mercat;Jama,2008

5. ¢ ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome;The Acute Respiratory Distress Syndrome Network;New Engl. J. Med.,2000

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