Chemical synthesis of 7-oxygenated 12α-hydroxy steroid derivatives to enable the biochemical characterization of cytochrome P450 8B1, the oxysterol 12α-hydroxylase enzyme implicated in cardiovascular health and obesity
Author:
Funder
MAX AND MINNIE TOMERLIN VOELCKER FUND
NIH
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry
Reference23 articles.
1. Purification and characterization of 7alpha-Hydroxy-4-cholesten-3-one 12alpha-monooxygenase;Murakami;J. Biol. Chem.,1982
2. Purification and characterization of 7alpha-hydroxy-4-cholesten-3-one 12alpha-hydroxylase;Ishida;J. Biol. Chem.,1992
3. Beyond intestinal soap – bile acids in metabolic control;Kuipers;Nat. Rev. Endocrinol.,2014
4. Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B Type I-deficient mice;Mardones;J. Lipid Res.,2001
5. Cyp8b1 ablation prevents Western diet-induced weight gain and hepatic steatosis because of impaired fat absorption;Bertaggia;Am. J. Physiol. Endocrinol. Metab.,2017
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Process intensification enhanced continuous flow for the effective coupling of sterol electrooxidation with H2 evolution using NiMo-based electrocatalysts;Chemical Engineering Science;2024-03
2. Synthesis of menarandroside A from dehydroepiandrosterone;Organic & Biomolecular Chemistry;2023
3. Copper oxidation chemistry using a 19-iminopyridine-bearing steroidal ligand: (i) C5-C6 olefin difunctionalization and (ii) C1β-hydroxylation/C19-peroxidation;Steroids;2022-10
4. Metal-Catalyzed C–H Bond Oxidation in the Total Synthesis of Natural and Unnatural Products;Synthesis;2022-08-04
5. A synthesis of a rationally designed inhibitor of cytochrome P450 8B1, a therapeutic target to treat obesity;Steroids;2022-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3