Paeonia lactiflora root extract suppresses cancer cachexia by down-regulating muscular NF-κB signalling and muscle-specific E3 ubiquitin ligases in cancer-bearing mice

Author:

Bae Taehyun,Jang Jaewoong,Lee Hyunji,Song Jaewon,Chae Seyeon,Park Minwoo,Son Chang-Gue,Yoon Seokmin,Yoon Yoosik

Funder

National Research Foundation

Chung-Ang University

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference42 articles.

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2. Animal models of the cancer anorexia-cachexia syndrome;Bennani-Baiti;Support. Care Cancer,2011

3. Megestrol acetate for the treatment of anorexia-cachexia syndrome;Berenstein;Cochrane Database Syst. Rev.,2005

4. Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1;Bodine;Am. J. Physiol. Endocrinol. Metab.,2014

5. IKKbeta/NF-kappaB activation causes severe muscle wasting in mice;Cai;Cell,2004

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