20S-Ginsenoside Rh2, the major bioactive saponin in Panax notoginseng flowers, ameliorates cough by inhibition of NaV1.7 and TRPV1 channel currents and downregulation of TRPV1 expression-Reference-Cited by-同舟云学术

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20S-Ginsenoside Rh2, the major bioactive saponin in Panax notoginseng flowers, ameliorates cough by inhibition of NaV1.7 and TRPV1 channel currents and downregulation of TRPV1 expression

Published:2025-01 Issue: Volume:336 Page:118716
ISSN:0378-8741
Container-title:Journal of Ethnopharmacology
language:en
Short-container-title:Journal of Ethnopharmacology

Author:

Liu Xiao,Xiang Jie^ORCID,Fan Shuyuan^ORCID,Chen Xumin,Peng Chengzhan,Xu Zhengxin^ORCID

Funder

National Natural Science Foundation of China

Foundation for Innovative Research Groups of the National Natural Science Foundation of China

Publisher

Elsevier BV

Reference73 articles.

1. Capsaicin, the vanilloid receptor TRPV1 agonist in neuroprotection: mechanisms involved and significance;Abdel-Salam;Neurochem. Res.,2023

2. A randomized controlled trial to assess the effect of lidocaine administered via throat spray and nebulization in patients with refractory chronic cough;Abdulqawi;J. Allergy Clin. Immunol. Pract.,2021

3. Chinese national guideline on diagnosis and management of cough(2021);Asthma Group of Chinese Thoracic;Zhonghua Jiehe He Huxi Zazhi,2022

4. XEN-D0501, a novel transient receptor potential vanilloid 1 antagonist, does not reduce cough in patients with refractory cough;Belvisi;Am. J. Respir. Crit. Care Med.,2017

5. The effect of the voltage-gated sodium channel Na(V)1.7 blocker PF-05089771 on cough in the Guinea pig;Brozmanova;Respir. Physiol. Neurobiol.,2022

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