Targeting in silico GPCR conformations with ultra-large library screening for hit discovery
Author:
Funder
National Institutes of Health
Deutsche Forschungsgemeinschaft
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference70 articles.
1. Mapping of the available chemical space versus the chemical universe of lead-like compounds;Lin;ChemMedChem,2018
2. Allosteric ‘beta-blocker’ isolated from a DNA-encoded small molecule library;Ahn;Proc. Natl. Acad. Sci. U. S. A.,2017
3. DNA-encoded chemistry: enabling the deeper sampling of chemical space;Goodnow;Nat. Rev. Drug Discov.,2017
4. High-power screening (HPS) empowered by DNA-encoded libraries;Sunkari;Trends Pharmacol. Sci.,2022
5. Reflections on DNA-encoded chemical libraries;Lerner;Biochem. Biophys. Res. Commun.,2020
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Functional consequences of spatial, temporal and ligand bias of G protein-coupled receptors;Nature Reviews Nephrology;2024-07-22
2. Illuminating the neuropeptide Y4 receptor and its ligand pancreatic polypeptide from a structural, functional, and therapeutic perspective;Neuropeptides;2024-06
3. Revolutionizing GPCR–ligand predictions: DeepGPCR with experimental validation for high-precision drug discovery;Briefings in Bioinformatics;2024-05-23
4. Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer’s disease;Cell Reports;2024-05
5. Revolutionizing GPCR-Ligand Predictions: DeepGPCR with experimental Validation for High-Precision Drug Discovery;2024-02-26
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3