Synthesis of 2′-fluoro-5-[11C]-methyl-1-β-d-arabinofuranosyluracil ([11C]-FMAU): A potential nucleoside analog for in vivo study of cellular proliferation with PET

Author:

Conti Peter S.,Alauddin Mian M.,Fissekis John R.,Schmall Bernard,Watanabe Kyochi A.

Publisher

Elsevier BV

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Molecular Medicine

Reference46 articles.

1. Phase I trial of 1-(2′-deoxy-2′-fluoro-1-β-d-arabinofuranosyl)-5-methyluracil (FMAU) terminated by severe neurologic toxicity;Abbruzzese;Invest. New Drugs,1989

2. A novel synthesis suitable for labeling the antiviral agent 9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]guanine (FHPG) with [18F] for in vivo imaging by positron emission tomography;Alauddin,1993

3. Synthesis of high specific activity [11C-methyl]-thymidine for in vivo imaging by positron emission tomography;Alauddin,1993

4. Synthesis of 2′-fluoro-5-[11C-methyl]-1-β-d-arabinofuranosyluracil ([11C]-FMAU) for use in in vivo imaging by positron emission tomography;Alauddin,1994

5. Selective alkylation of pyrimidyl dianions II: Synthesis, characterization and comparative reactivity of 3′,5′-o-bis tetrahydropyranyl, trimethylsilyl, and t-butyldimethylsilyl derivatives of 5-bromodeoxyuridine;Alauddin;Tetrahedron,1994

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