Combined Surgery and Radiation Therapy for Squamous Cell Carcinoma of the Hypopharynx-Reference-Cited by-同舟云学术

Combined Surgery and Radiation Therapy for Squamous Cell Carcinoma of the Hypopharynx

Published:1997-06 Issue:6 Volume:116 Page:637-641
ISSN:0194-5998
Container-title:Otolaryngology–Head and Neck Surgery
language:en
Short-container-title:Otolaryngol Head Neck Surg

Author:

Kraus Dennis H.¹,Zelefsky Michael J.²,Brock Heidi A. J.¹,Huo Jerry¹,Harrison Louis B.²,Shah Jatin P¹

Affiliation:

1. Head and Neck Service, Department of Surgery, and the Brachytherapy Service, New York, New York

2. Department of Radiation Therapy, Memorial Sloan-Kettermg Cancer Center, New York, New York

Abstract

Squamous cell carcinoma of the hypopharynx remains a highly lethal disease. This article documents our experience with 132 patients undergoing surgical management of squamous cell carcinoma of the hypopharynx, of whom 80% received postoperative radiation therapy. Local-regional control was obtained in 61% of the patients. Five-year overall and disease-free survival rates were 30% and 41%, respectively. Prognosis was better in patients with limited disease: local disease permitting larynx-sparing surgery, N0/N1 clinical neck, and stage I/II/III disease. Cancer of the hypopharynx remains an aggressive entity associated with poor prognosis. Novel strategies stressing improved local-regional control with prevention of distant metastasis are warranted.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1016/S0194-5998%2897%2970240-7

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