Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-κB) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes

Author:

Liacini Abdelhamid,Sylvester Judith,Li Wen Qing,Zafarullah Muhammad

Publisher

Elsevier BV

Subject

Molecular Biology

Reference58 articles.

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3. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function;Badger;J. Pharmacol. Exp. Ther.,1996

4. Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage;Billinghurst;J. Clin. Invest.,1997

5. Nuclear factor kappaB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabbit dermal fibroblasts;Bond;Biochem. Biophys. Res. Commun.,1999

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