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The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes

  • Published:2019-07 Issue:2 Volume:50 Page:212-228.e6
  • ISSN:1534-5807
  • Container-title:Developmental Cell
  • language:en
  • Short-container-title:Developmental Cell

Author:

Bowen Margot E.,McClendon Jacob,Long Hannah K.,Sorayya Aryo,Van Nostrand Jeanine L.,Wysocka Joanna,Attardi Laura D.

Funder

March of Dimes Foundation

Jane Coffin Childs Fund

Stanford Child Health Research Institute

Sir Henry Wellcome

Howard Hughes Medical Institute

Ludwig Foundation

Stinehart/Reed

Publisher

Elsevier BV

Subject

Developmental Biology,Cell Biology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology

Reference94 articles.

1. The Ensembl gene annotation system;Aken;Database,2016

2. HTSeq–a Python framework to work with high-throughput sequencing data;Anders;Bioinformatics,2015

3. PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family;Attardi;Genes Dev.,2000

4. CHD7 cooperates with PBAF to control multipotent neural crest formation;Bajpai;Nature,2010

5. iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53;Bergamaschi;Nat. Genet.,2006
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