Population Pharmacokinetic and Exposure–Response Model Simulations: Predicted Exposure and Efficacy for Maintenance Doses of Intravenous Golimumab Every 6 or 8 Weeks in Patients With Moderately to Severely Active Rheumatoid Arthritis

Author:

Lee Jong Bong,Broadwell AaronORCID,Fan Yijun,Hu Chuanpu,Adedokun Omoniyi J.,Chakravarty Soumya D.,Zhou Honghui,Xu Zhenhua,Leu Jocelyn H.

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmacology

Reference13 articles.

1. Diagnosis and management of rheumatoid arthritis;Wasserman;Am Fam Physician,2011

2. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update;Smolen;Ann Rheum Dis,2020

3. Simponi Aria. United States Prescribing Information. Janssen; 2019. Accessed April 29, 2021. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/125433s028lbl.pdf

4. Simponi Aria. Canadian Consumer Information. Janssen; 2019. Accessed July 23, 2021. https://www.janssen.com/canada/sites/www_janssen_com_canada/files/prod_files/live/simponi_ci.pdf

5. Pharmacokinetics and safety of golimumab, a fully human anti-TNF-alpha monoclonal antibody, in subjects with rheumatoid arthritis;Zhou;J Clin Pharmacol,2007

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