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Trimetazidine prevents diabetic cardiomyopathy by inhibiting Nox2/TRPC3-induced oxidative stress

  • Published:2019-04 Issue:4 Volume:139 Page:311-318
  • ISSN:1347-8613
  • Container-title:Journal of Pharmacological Sciences
  • language:en
  • Short-container-title:Journal of Pharmacological Sciences

Author:

Tang Sheng-Gao,Liu Xiao-Yu,Wang Shan-Ping,Wang Hong-Hui,Jovanović Aleksandar,Tan Wen

Funder

Fundamental Research Funds for the Central Universities

Special Fund for Public Welfare Research and Capacity Building of Guangdong Province

University of Nicosia Medical School

Publisher

Elsevier BV

Subject

Pharmacology,Molecular Medicine

Reference31 articles.

1. New type of cardiomyopathy associated with diabetic glomerulosclerosis;Rubler;Am J Cardiol,1972

2. Role of diabetes in congestive heart failure: the Framingham study;Kannel;Am J Cardiol,1974

3. Molecular mechanisms of diabetic cardiomyopathy;Bugger;Diabetologia,2014

4. Nox2 contributes to cardiac fibrosis in diabetic cardiomyopathy in a transforming growth factor-β dependent manner;Liu;Int J Clin Exp Pathol,2015

5. TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling;Kitajima;Sci Rep,2016

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