First-in-human, double-blind, placebo-controlled, single-dose escalation study of aducanumab (BIIB037) in mild-to-moderate Alzheimer's disease
Author:
Affiliation:
1. Biogen; Cambridge MA USA
Funder
Biogen
Complete Medical Communications
Publisher
Wiley
Subject
Psychiatry and Mental health,Clinical Neurology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/j.trci.2016.06.002/fullpdf
Reference22 articles.
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2. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics;Hardy;Science,2002
3. Alzheimer's disease: the amyloid cascade hypothesis;Hardy;Science,1992
4. Biological markers of amyloid beta-related mechanisms in Alzheimer's disease;Hampel;Exp Neurol,2010
5. Amyloid ß deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study;Villemagne;Lancet Neurol,2013
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