Morita-Baylis-Hillman adduct 2-(3-hydroxy-1-methyl-2-oxoindolin-3-il) acrylonitrile (CISACN) ameliorates the pulmonary allergic inflammation in CARAS model by increasing IFN-γ/IL-4 ratio towards the Th1 immune response

Author:

Adilis Maria Paiva Ferreira Larissa,Karla Diega Paiva Ferreira Laércia,Fragoso Pereira Cavalcanti Raquel,Allysson de Assis Ferreira Gadelha Francisco,Mangueira de Lima Louise,Francisco Alves Adriano,Gabriel Lima Júnior Cláudio,Regina Piuvezam Marcia

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Elsevier BV

Reference35 articles.

1. Combined allergic rhinitis and asthma syndrome (CARAS);Paiva Ferreira;Int. Immunopharmacol.,2019

2. The Allergic Rhinitis and Its Impact on Asthma (ARIA) Approach of Value-Added Medicines: As-Needed Treatment in Allergic Rhinitis;Bousquet;J. Allergy Clin. Immunol. Pract.,2022

3. Correlation between upper and lower airway inflammations in patients with combined allergic rhinitis and asthma syndrome: A comparison of patients initially presenting with allergic rhinitis and those initially presenting with asthma;Xia;Exp. Ther. Med.,2018

4. The Burden of Asthma and Allergic Rhinitis;Patel;Otolaryngol. Clin. North Am.,2023

5. 4-Carvomenthenol ameliorates the murine combined allergic rhinitis and asthma syndrome by inhibiting IL-13 and mucus production via p38MAPK/NF-κB signaling pathway axis;Bezerra Barros;Int. Immunopharmacol.,2020

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