A hydrogen peroxide-activated Cu(II) pro-ionophore strategy for modifying naphthazarin as a promising anticancer agent with high selectivity for generating ROS in HepG2 cells over in L02 cells
Author:
Funder
National Natural Science Foundation of China
111 Project
Publisher
Elsevier BV
Subject
Physiology (medical),Biochemistry
Reference46 articles.
1. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?;Trachootham;Nat. Rev. Drug Discov.,2009
2. Modulation of oxidative stress as an anticancer strategy;Gorrini;Nat. Rev. Drug Discov.,2013
3. Lysosome-targeting amplifiers of reactive oxygen species as anticancer prodrugs;Daum;Angew. Chem. Int. Ed.,2017
4. Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH;Yun;Science,2015
5. Oxidative stress inhibits distant metastasis by human melanoma cells;Piskounova;Nature,2015
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Boronate-based bioactive compounds activated by peroxynitrite and hydrogen peroxide;Redox Biochemistry and Chemistry;2024-12
2. Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress;Environmental Pollution;2024-07
3. Cuprous oxide nanocomposites with photothermal (PTT) and chemical dynamics (CDT) effects induce cuproptosis in breast cancer using the strategy of increasing inflow and reducing outflow;Nano Today;2024-06
4. Cuproptosis: emerging biomarkers and potential therapeutics in cancers;Frontiers in Oncology;2023-11-07
5. Dissecting copper biology and cancer treatment: ‘Activating Cuproptosis or suppressing Cuproplasia’;Coordination Chemistry Reviews;2023-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3