Beyond repression of Nrf2: An update on Keap1-Reference-Cited by-同舟云学术

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Beyond repression of Nrf2: An update on Keap1

Published:2020-09 Issue: Volume:157 Page:63-74
ISSN:0891-5849
Container-title:Free Radical Biology and Medicine
language:en
Short-container-title:Free Radical Biology and Medicine

Author:

Kopacz Aleksandra,Kloska Damian,Forman Henry Jay,Jozkowicz Alicja,Grochot-Przeczek Anna

Funder

National Science Centre

United States National Institutes of Health

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference193 articles.

1. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements;Itoh;Biochem. Biophys. Res. Commun.,1997

2. Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis;Malhotra;Nucleic Acids Res.,2010

3. Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex;Baird;Proc. Natl. Acad. Sci. U. S. A.,2013

4. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain;Itoh;Genes Dev.,1999

5. The KEAP1-NRF2 system: a thiol-based sensor-effector apparatus for maintaining redox homeostasis;Yamamoto;Physiol. Rev.,2018

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4. The role of Keap1-Nrf2 signaling pathway in the treatment of respiratory diseases and the research progress on targeted drugs;Heliyon;2024-09

5. Genome-Wide CRISPR Screen Identifies KEAP1 Perturbation as a Vulnerability of ARID1A-Deficient Cells;Cancers;2024-08-24

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