The emerging role of Nrf2 in mitochondrial function
Author:
Funder
Cancer Research UK
BBSRC
Wellcome Trust/MRC
Publisher
Elsevier BV
Subject
Physiology (medical),Biochemistry
Reference110 articles.
1. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain;Itoh;Genes Dev.,1999
2. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase;Cullinan;Mol. Cell. Biol.,2004
3. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2;Kobayashi;Mol. Cell. Biol.,2004
4. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex;Zhang;Mol. Cell. Biol.,2004
5. Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex;Baird;Proc. Natl. Acad. Sci. USA,2013
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