Indomethacin inactivates gastric peroxidase to induce reactive-oxygen-mediated gastric mucosal injury and curcumin protects it by preventing peroxidase inactivation and scavenging reactive oxygen

Author:

Chattopadhyay Ishita,Bandyopadhyay Uday,Biswas Kaushik,Maity Pallab,Banerjee Ranajit K.

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference79 articles.

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2. Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanism;Milller;Am. J. Physiol.,1983

3. Increased microvascular permeability and lesion formation during gastric hypermotility caused by indomethacin and 2-deoxy-D-glucose in rat;Takeuchi;J. Clin. Gastroenterol.,1990

4. Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil dependent process;Wallace;Am. J. Physiol.,1990

5. Induction of Tumor Necrosis Factor-α and apoptosis in gastric mucosal injury by indomethacin: effect of omeprazole and ebrotidine;Slomiany;Scand. J. Gastroenterol.,1997

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