The Elabela-APJ axis attenuates sepsis-induced myocardial dysfunction by reducing pyroptosis by balancing the formation and degradation of autophagosomes

Author:

Liu Shuai,Liu Fu-Zhong,Yan Jue-Yue,Fang Xing,Xu Zhi-Peng,Cai Hong-Liu,Yang Ying-Jun,Yu Yong-WeiORCID

Funder

Medical and Health Research Project of Zhejiang Province

Natural Science Foundation of Zhejiang Province

Publisher

Elsevier BV

Reference33 articles.

1. Pathophysiology of sepsis-induced myocardial dysfunction;Xiuxiu;Mil Med Res,2016

2. Sepsis: current dogma and new perspectives;Clifford S;Immunity,2014

3. Phlorizin, a novel caloric restriction mimetic, stimulates hypoxia and protects cardiomyocytes through activating autophagy via modulating the Hif-1α/Bnip3 axis in sepsis-induced myocardial dysfunction;Yong-Wei;Int. Immunopharm.,2023

4. Loss of hepatic angiotensinogen attenuates sepsis-induced myocardial dysfunction;Jiabing;Circ. Res.,2021

5. Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction;Gabriel;Crit. Care,2023

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