Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice

Author:

Evans Charles E.,Thomas Rhian S.,Freeman Thomas J.,Hvoslef-Eide Martha,Good Mark A.ORCID,Kidd Emma J.

Funder

School of Psychology Cardiff and the Cardiff School of Pharmacy and Pharmaceutical Sciences

Wellcome Trust PhD studentship

Life Science Research Network Wales

Alzheimer’s Society UK PhD studentship

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Neurology (clinical),Aging,General Neuroscience

Reference48 articles.

1. Alzheimer’s Disease Facts and Figures;Alzheimer’s Dement. J. Alzheimer's Assoc.,2015

2. Inhibition of amyloid precursor protein processing by β-secretase through site-directed antibodies;Arbel;Proc. Natl. Acad. Sci U. S. A.,2005

3. Immunomodulation of AβPP processing alleviates amyloid-β-related pathology in Alzheimer’s disease transgenic mice;Arbel-Ornath;J. Alzheimer’s Dis.,2009

4. Object-in-place associative recognition memory depends on glutamate receptor neurotransmission within two defined hippocampal-cortical circuits: a critical role for AMPA and NMDA receptors in the hippocampus, perirhinal, and prefrontal cortices;Barker;Cereb. Cortex,2013

5. When is the hippocampus involved in recognition memory?;Barker;J. Neurosci,2011

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