Pyroglutamate-Modified Amyloid- β (3–42) Shows α -Helical Intermediates before Amyloid Formation-Reference-Cited by-同舟云学术

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Pyroglutamate-Modified Amyloid- β (3–42) Shows α -Helical Intermediates before Amyloid Formation

Published:2017-04 Issue:8 Volume:112 Page:1621-1633
ISSN:0006-3495
Container-title:Biophysical Journal
language:en
Short-container-title:Biophysical Journal

Author:

Dammers Christina,Reiss Kerstin,Gremer Lothar,Lecher Justin,Ziehm Tamar,Stoldt Matthias,Schwarten Melanie,Willbold Dieter

Funder

International NRW Research School BioStruct

Ministry of Innovation, Science and Research of the State North Rhine-Westphalia

Heinrich Heine University Düsseldorf

Entrepreneur Foundation at the Heinrich Heine University Düsseldorf

Impuls- und Vernetzungs-Fonds der Helmholtzgemeinschaft

Publisher

Elsevier BV

Subject

Biophysics

Reference70 articles.

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2. Alzheimer mechanisms and therapeutic strategies;Huang;Cell,2012

3. The secretases: enzymes with therapeutic potential in Alzheimer disease;De Strooper;Nat. Rev. Neurol.,2010

4. Pyroglutamate-Aβ: role in the natural history of Alzheimer’s disease;Gunn;Int. J. Biochem. Cell Biol.,2010

5. Pyroglutamate amyloid-β (Aβ): a hatchet man in Alzheimer disease;Jawhar;J. Biol. Chem.,2011

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1. Targeting the hydrophobic region of pyroglutamate‐modified amyloid‐β by tyrocidine A prevents its nucleation–aggregation process and its “catalytic effect” on the Aβs aggregation;Journal of Biochemical and Molecular Toxicology;2024-08

2. Conformation of Pyroglutamated Amyloid β (3–40) and (11–40) Fibrils – Extended or Hairpin?;The Journal of Physical Chemistry B;2024-02-09

3. Amyloid-α Peptide Formed through Alternative Processing of the Amyloid Precursor Protein Attenuates Alzheimer’s Amyloid-β Toxicity via Cross-Chaperoning;Journal of the American Chemical Society;2024-01-18

4. Structural Impact of N‐terminal Pyroglutamylate in an Amyloid‐β(3‐42) Fibril Probed by Solid‐State NMR Spectroscopy;Chemistry – A European Journal;2023-12-29

5. Modulation of aggregation and structural polymorphisms of β-amyloid fibrils in cellular environments by pyroglutamate-3 variant cross-seeding;Journal of Biological Chemistry;2023-10

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