Little in vitro effect of remdesivir on mitochondrial respiration and monoamine oxidase activity in isolated mitochondria

Author:

Fišar ZdeněkORCID,Ľupták MatejORCID,Hroudová JanaORCID

Funder

Univerzita Karlova v Praze

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference69 articles.

1. Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease;Agostini;mBio,2018

2. Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics;Akinci;bioRxiv,2020

3. Pharmacological approaches to restore mitochondrial function;Andreux;Nat. Rev. Drug Discov.,2013

4. Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes;Baldwin;J. Biol. Chem.,2005

5. Remdesivir for the treatment of Covid-19 - final report;Beigel;N. Engl. J. Med.,2020

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