Identification of 2-chloro-2-deoxyglucose (2-CIDG) and d-glucose as impurities formed in the synthesis of 2-18F]Fluoro-2-deoxyglucose (2-18FDG)

Author:

Chaar M.R.,Dufek P.,Favre-Bonvin J.,Landais P.G.,Le Bars D.,Galy G.,Porthault M.

Publisher

Elsevier BV

Subject

Radiation

Reference6 articles.

1. Ion chromatographic analysis of 18FDG produced by [18F]fluoride dislacement: production of 2-chloro-2-deoxy-D-glucose as an impurity in the presence of chloride ion;Alexoff;J. Label. Comp. Radiopharm.,1991

2. A large scale manual production of [18]FDG using a synthetic unit made of sterile disposable components and operated by a Master Slave manipulator;Chaly;Appl. Radiat. Isot.,1990

3. Recommendation for a practical production of (2-18F) fluoro-2-deoxy-d-glucose;Coenen;Appl. Radiat. Isot.,1987

4. Efficient stereospecific synthesis of no-carrier added 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution;Hamacher;J. Nucl. Med.,1986

5. Gaz-liquid chromatographic determination of relative amounts of 2-deoxy-2-fluoro-D-glucose and 2-deoxy-2-fluoro-D-mannose synthetized from various methods;Shiue;J. Label. Compds Radiopharm.,1984

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