Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment

Author:

Dourson Michael,Reichard John,Nance Patricia,Burleigh-Flayer Heather,Parker Ann,Vincent Melissa,McConnell Ernest E.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference48 articles.

1. Studies on the carcinogenic activity of protein-denaturing agents: hepatocarcinogenicity of dioxane;Argus;J. Natl. Cancer Inst.,1965

2. Dose–response and ultrastructural alterations in dioxane carcinogenesis;Argus;Eur. J. Cancer,1973

3. ATSDR (Agency for Toxic Substances and Disease Registry), 2007. Toxicological Profile for 1,4-Dioxane. Draft for Public Comment. Atlanta, GA. Available at: .

4. Haemorrhagic nephritis and necrosis of the liver from dioxin poisoning;Barber;Guy’s Hosp. Rep.,1934

5. Association of carcinoma yield with early papilloma development in SENCAR mice;Bull;Environ. Health Perspect.,1986

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