Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability

Author:

Ates GamzeORCID,Steinmetz Fabian P.,Doktorova Tatyana Yordanova,Madden Judith C.,Rogiers Vera

Funder

Vrije Universiteit Brussel

Scientific Institute of Public Health, Belgium

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference15 articles.

1. An interesting relationship between drug absorption and melting point;Chu;Int. J. Pharm.,2009

2. Review of the availability of in vitro and in silico methods for assessing dermal bioavailability;Dumont;Appl. In Vitro Toxicol.,2015

3. Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products;2009/1223/EC;Off. J.,2009

4. Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients;Kroes;Food Chem. Toxicol.,2007

5. A prediction model for oral bioavailability of drugs using physicochemical properties by support vector machine;Kumar;J. Nat. Sci. Biol. Med.,2011

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