Insulin induces IRS2-dependent and GRK2-mediated β2AR internalization to attenuate βAR signaling in cardiomyocytes
Author:
Funder
National Natural Science Foundation of China
Central Authorities of an Institution of Higher Learning of Scientific Research Special Fund of China
NIH
Publisher
Elsevier BV
Subject
Cell Biology
Reference22 articles.
1. Physiological Regulation of G Protein-Linked Signaling
2. G-Protein-Linked Receptors as Substrates for Tyrosine Kinases: Cross-Talk in Signaling
3. Insulin Stimulates Sequestration of β-Adrenergic Receptors and Enhanced Association of β-Adrenergic Receptors with Grb2 via Tyrosine 350
4. Serum and Insulin Induce a Grb2-Dependent Shift in Agonist Affinity of β-Adrenergic Receptors
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