Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans

Author:

Shono Yasushi,Jantratid Ekarat,Kesisoglou Filippos,Reppas Christos,Dressman Jennifer B.

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Medicine,Biotechnology

Reference48 articles.

1. The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human;Wu;Int. J. Pharm.,2004

2. US FDA. Guidance for Industry: Waiver of in vivo bioavailability and bioequivalence studies for immediate-release solid oral dosage forms based on a biopharmaceutics classification system, 2000.

3. Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards;Löbenberg;Eur. J. Pharm. Biopharm.,2000

4. Drug, meal and formulation interactions influencing drug absorption after oral administration. Clinical implications;Fleisher;Clin. Pharmacokinet.,1999

5. Effects of food on clinical pharmacokinetics;Singh;Clin. Pharmacokinet.,1999

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